Environment and Breast Cancer: Science Review


Search the Mammary Carcinogens Reviews Database

1,2-dichloropropane
CAS RN 78-87-5



Cancer studies: Mammary gland tumors
Print this page
Originating list
The list(s) or database(s) in which the chemical was identified as showing an increase in mammary gland tumors. CPDB: Carcinogenic Potency Database, IARC: International Agency for Research on Chemicals Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man summaries, NTP TR: National Toxicology Program (NTP) Technical Reports, NTP 11ROC: NTP 11th Report on Carcinogens, CCRIS: Chemical Carcinogenesis Research Information Service.
National Toxicology Program studies, Chemical Carcinogenesis Research Information System
Mammary gland tumor summary
A summary of findings related to mammary gland tumors, most often excerpted from IARC Monographs or the NTP 11th ROC, and, in some cases, supplemented by our evaluation of individual studies and reviews, is available for the priority chemicals and 67 others.
One NTP study reported mammary tumors.
Citations to review sources and individual studies reporting mammary gland tumors are listed below.
Citation
Source Type
Notes
International Agency for Research on Cancer, Monographs on the evaluation of carcinogenic risk of chemicals to man.VOL.: 71 (1999) (p. 1393) 1,2-Dichloropropane.
Review
Only summarizes IARC 1986 (though none mentioned in summary.) v41, p131
Carcinogenic Potency Database 2005. Gold LS ST, Manley NB, Garfinkel GB, Ames BN. Summary Table by Chemical of Carcinogenicity Results in CPDB on 1485 Chemicals. 2005
Review
One of one study reports mammary tumors: NTP TR263.
National Toxicology Program Technical Report 263, 1986
Primary Literature
National Toxicology Program 11th Report on Carcinogens, Table 1. Chemicals nominated to the National Toxicology Program for in-depth toxicological evaluation for carcinogenesis testing in fiscal years 1988-2003.
Review
Nominated by State of California 1995. Rationale: Data gaps that should be filled in order to set scientifically based acute and chronic non-cancer reference exposure levels for use in human and environmental risk assessments. Current NTP Status: No additional testing.