Environment and Breast Cancer: Science Review
47 pharmaceuticals, including synthetic hormones, chemotherapeutic drugs, and urinary tract infection treatments, have been shown to cause mammary tumors in laboratory animals.
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1,2-dibromoethane
1,2-propylene oxide
1,3-butadiene
1,4-dioxane
2,2-bis(bromomethyl)-1,3-propanediol
2,3-dibromo-1-propanol
2,4-diaminotoluene
2,4-dinitrotoluene
2-chloroacetophenone
2-methylaziridine
4,4 '-methylene-bis(2-chloroaniline)
5-nitroacenaphthene
acrylamide
acrylonitrile
AF-2 (2-(2-furyl)-3-(5-nitro-2-furyl) acrylamide)
benzene
chloroprene
ethylene oxide
glycidol
hydrazine
hydrazobenzene
indium phosphide
nitrobenzene
nitromethane
n-nitroso-di-n-butylamine
o-nitrotoluene
ortho-aminoazotoluene
ortho-toluidine hydrochloride
perfluorooctanoic acid
propane sultone
styrene
toluene diisocyanate mixtures
urethane
vinyl chloride
vinyl fluoride
vinylidene chloride
1,1-dichloroethane
1,2,3-trichloropropane
1,2-dichloroethane
1,2-dichloropropane
carbon tetrachloride
methylene chloride
1,3-dinitropyrene
1,8-dinitropyrene
1-nitropyrene
2-aminoanthracene
2-nitrofluorene
3-amino-1-methyl-5h-pyrido[4,3-b]indole
3-methylcholanthrene
4-nitropyrene
6-nitrochrysene
7,12-dimethylbenz[a]anthracene
benzo[a]pyrene
dibenz[a,h]anthracene
dibenzo[def,p]chrysene
IQ
isoprene
MeIQ
PhIP
Trp-P-2 acetate
1,2-dibromo-3-chloropropane
atrazine
captafol
chlordane
clonitralid
dichlorvos
fenvalerate
nifurthiazole
simazine
sulfallate
2,4-diaminoanisole sulfate
3,3'-dichlorobenzidine
3,3'-dimethoxybenzidine
3,3'-dimethylbenzidine
4,4 '-methylene-bis(2-methylaniline)
4-aminobiphenyl
5-nitro-ortho-anisidine
amsonic acid
benzidine
C.I. Acid Red 114
C.I. Basic Red 9 monohydrochloride
C.I. Direct Black 38
FD&C Violet no. 1
Guinea Green B
HC Yellow no. 3
leucomalachite green
malachite green
n,n'-diacetylbenzidine
MX (3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone)
magnetic fields
neutrons
radionuclide hydrogen-3
x-rays, gamma rays (ionizing radiation)
1-(2-hydroxyethyl)- 3 -[(5- nitrofurfurylidene )amino]-2-imidazolidinone
1,2- dimethyl-5-nitroimidazole
1-[(5-nitrofurfurylidene)amino]-2-imidazolidinone
2-amino-5-(5-nitro-2-furyl)-1,3,4-oxadiazole
2-amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole
2-amino-5-nitrothiazole
4,4 '-sulfonylbisacetanilide
4-methyl-1-[(5-nitrofurfurylidene )amino ]-2-imidazolidinone
5-(morpholinomethyl)-3-[(5-nitrofurfurylidene)-amino]-2-oxazolidinone - l form
5-azacytidine
acronycine
adriamycin
amsacrine
anti-(+/-)-trans-7,8,9,10-tetrahydrobenzo[a]pyrene-7,8-diol-9,10-epoxide
bemitradine
chloroambucil
cyclophosphamide
cytembena
dacarbazine
daunomycin
dibromomannitol
furosemide
griseofulvin
hexamethylmelamine
indomethacin
isoniazid
isonicotinic acid vanillylidenehydrazide
isophosphamide
l-5-morpholinomethyl- 3-[ (5-nitrofurfurylidene )amino ]-2-oxazolidinone.hcl
merphalan
metronidazole
mitomycin-c
n,n'-dimethylnitrosourea
n-[4-(5-nitro-2-furyl)-2-thiazolyl]acetamide
niridazole
nithiazide
nitrofurantoin
nitrofurazone
norlestrin
phenacetin
phenesterin
procarbazine hydrochloride
reserpine
SQ 18506
thiotepa
trans-2-[(dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole
uracil mustard
17a-hydroxyprogesterone caproate
chlormadinone acetate
conjugated estrogens
diethylstilbestrol
estradiol-17b
estriol
estrone
ethinylestradiol
ethynodial diacetate
lynestrenol
medroxyprogesterone acetate
megestrol acetate
mestranol
norethisterone
norethynodrel
progesterone
testosterone
bracken fern (and its extracted chemicals)
carboxymethylnitrosourea
methyleugenol
ochratoxin A
wood dust methanol extract
1-amyl-1- nitrosourea
2-acetylaminofluorene
2-aminofluorene
3,2'-dimethyl-4-aminobiphenyl
4-(5-nitro-2-furyl) thiazole
4-bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl) quinazoline
4-hydroxyaminoquinoline 1-oxide hydrochloride
ethyl methanesulfonate
n-(4-(5-nitro-2-furyl)-2-thiazolyl) formamide
n-(9-oxo-2-fluorenyl)acetamide
n,n'-diethyl-n-nitrosourea
n-n-butyl-n-nitrosourea
n-nitroso-n-ethylurea
n-nitroso-n-methylurea
vinyl carbamate epoxide
(n-6)-(methylnitroso)adenosine
1-(2-hydroxyethyl)-1-nitrosourea
1-(2-hydroxyethyl)-nitroso-3-ethylurea
1,3-dibutyl-1-nitrosourea
1-allyl-1-nitrosourea
1-ethylnitroso-3-(2-hydroxyethyl)-urea
1-ethylnitroso-3-(2-oxopropyl)-urea
2-(2,2-dimethylhydrazino)-4-(5-nitro-2-furyl) thiazole
2,2,2-trifluoro-n-[4-(5-nitro-2-furyl)-2-thiazolyl] acetamide
2-hydrazino-4-(5-nitro-2-furyl) thiazole
2-hydrazino-4-(p-aminophenyl) thiazole
2-hydrazino-4-(p-nitrophenyl) thiazole
2-methoxy-3-aminodibenzofuran
3-(5-nitro-2-furyl)-imidazo(1,2-a) pyridine
4,6-diamino-2-(5-nitro-2-furyl)-s-triazine
4,6-dimethyl-2-(5-nitro-2-furyl) pyrimidine
4-acetylaminobiphenyl
4-aminostilbene
anti-(+/-)-1,2,3,4-tetrahydrobenzo[c]phenanthrene-3,4-diol-1,2-epoxide
anti-1,2,3,10b-tetrahydrofluoranthene-2,3-diol 1,10b-oxide
anti-4,5-dihydroxy-6,6a-epoxy-4,5,6,6a-tetrahydrobenzo[j]fluoranthene
anti-9,10-dihydroxy-11,12-epoxy-9,10,11,12-tetrahydrobenzo[j]fluoranthene
anti-benzo[a]chrysene-11,12-diol-13,14-epoxide
anti-dibenzo[a,l]pyrene-11,12-dihydrodiol-13,14-epoxide
azoxyethane
dimethylaminoethylnitrosoethylurea, nitrite salt
formic acid 2-(4-methyl-2-thiazolyl)hydrazide
methylhydrazine sulfate
n - hexylnitrosourea
n-(2-fluorenyl)-2,2,2-trifluoroacetamide
n-(n-methyl-n- nitrosocarbamoyl)-1-ornithine
n,n' -[ 6-( 5- nitro-2-furyl)-s-triazine- 2,4-diyl]bisacetamide
n-1-diacetamidofluorene
n-ethyl-n'-methyl-n-nitrosourea
n-hydroxy-2-(acetylamino)fluorene
n-hydroxy-n,n'-diacetylbenzidine
n-hydroxy-n-formyl-trans-4-aminostilbene
n-hydroxy-n-propionyl-trans-4-aminostilbene
trans-n-hydroxy-4-acetylaminostilbene