Environment and Breast Cancer: Science Review
Cancer studies: Mammary gland tumors
The list(s) or database(s) in which the chemical was identified as showing an increase in mammary gland tumors. CPDB: Carcinogenic Potency Database, IARC: International Agency for Research on Chemicals Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man summaries, NTP TR: National Toxicology Program (NTP) Technical Reports, NTP 11ROC: NTP 11th Report on Carcinogens, CCRIS: Chemical Carcinogenesis Research Information Service.IARC Monographs
Mammary gland tumor summary
A summary of findings related to mammary gland tumors, most often excerpted from IARC Monographs or the NTP 11th ROC, and, in some cases, supplemented by our evaluation of individual studies and reviews, is available for the priority chemicals and 67 others.IARC 1991: When administered orally, there was an increased incidence of benign mammary tumors in female rats in one study.
Citations to review sources and individual studies reporting mammary gland tumors are listed below.
International Agency for Research on Cancer, Monographs on the evaluation of carcinogenic risk of chemicals to man.VOL.: 53 (1991) (p. 309) Fenvalerate. Summary of Data Reported and Evaluation.
Carcinogenic Potency Database 2005. Gold LS ST, Manley NB, Garfinkel GB, Ames BN. Summary Table by Chemical of Carcinogenicity Results in CPDB on 1485 Chemicals. 2005
Parker CM, Patterson DR, Van Gelder GA, Gordon EB, Valerio MG, Hall WC. Chronic toxicity and carcinogenicity evaluation of fenvalerate in rats. J Toxicol Environ Health 1984;13(1):83-97.
Cabral JR, Galendo D. Carcinogenicity study of the pesticide fenvalerate in mice. Cancer Lett 1990;49(1):13-8.
Parker CM, McCullough CB, Gellatly JB, Johnston CD. Toxicologic and carcinogenic evaluation of Fenvalerate in the B6C3F1 mouse. Fundam Appl Toxicol 1983;3(2):114-20.
National Toxicology Program 11th Report on Carcinogens, Table 1. Chemicals nominated to the National Toxicology Program for in-depth toxicological evaluation for carcinogenesis testing in fiscal years 1988-2003.