Environment and Breast Cancer: Science Review

Search the Mammary Carcinogens Reviews Database

Guinea Green B
CAS RN 4680-78-8

Cancer studies: Mammary gland tumors
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Originating list
The list(s) or database(s) in which the chemical was identified as showing an increase in mammary gland tumors. CPDB: Carcinogenic Potency Database, IARC: International Agency for Research on Chemicals Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man summaries, NTP TR: National Toxicology Program (NTP) Technical Reports, NTP 11ROC: NTP 11th Report on Carcinogens, CCRIS: Chemical Carcinogenesis Research Information Service.
IARC Monographs
Mammary gland tumor summary
A summary of findings related to mammary gland tumors, most often excerpted from IARC Monographs or the NTP 11th ROC, and, in some cases, supplemented by our evaluation of individual studies and reviews, is available for the priority chemicals and 67 others.
IARC 1978: Following ambient (inhalation) exposure, produced benign mammary tumors in rats.
Citations to review sources and individual studies reporting mammary gland tumors are listed below.
Source Type
International Agency for Research on Cancer, Monographs on the evaluation of carcinogenic risk of chemicals to man.VOL.: 16 (1978) (p. 199) Guinea Green B. Summary of Data Reported and Evaluation.
Continual skin/fur contact induced benign mammry tumors in rats (sex unspecified): Mannell 1964.
Mannell WA, Grice HC, Dupuis I. The effect on rats of long term exposure to guinea green B and benzyl violet 4B. Fd Cosmet Toxicol. 1964;2:345-7.
Primary Literature
National Toxicology Program 11th Report on Carcinogens, Table 1. Chemicals nominated to the National Toxicology Program for in-depth toxicological evaluation for carcinogenesis testing in fiscal years 1988-2003.
Not nominated for NTP testing in 1998-2003.