Environment and Breast Cancer: Science Review

Evidence From Humans
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Drinking water and cancer mortality in Louisiana
Page, T., Harris, R. H., Epstein, S. S. Science. 1976. 193:4247, 55-7.
Topic area
Environmental pollutant - Drinking water
Study design
Other: Ecologic epidemiology
Funding agency
Not reported
Study Participants
Menopausal Status
The menopausal status of women included in this study is listed here.
Exposures investigated
Drinking water contaminants. Percent of the population drawing water from Mississippi River and its tributaries
How exposure was measured
GIS/geographic location
Breast cancer outcome investigated
Other: age-adjusted 20-year mortality by parish
Ethnic groups with separate analysis
If this study provided a separate analysis by ethnic or racial group, the groups are listed here.
Nonwhite, white
Confounders considered
Other breast cancer risk factors, such as family history, age at first birth, and hormone replacement therapy use, that were taken into account in the study.
Urbanicity, income, occupation by parish
Genetic characterization included
If the study analyzed relationships between environmental factors and inherited genetic variations, this field will be marked “Yes.” “No”, if not.
Description of major analysis
Least squares linear regression
Strength of associations reported
No significant association, association stronger for nonwhites