Environment and Breast Cancer: Science Review
47 pharmaceuticals, including synthetic hormones, chemotherapeutic drugs, and urinary tract infection treatments, have been shown to cause mammary tumors in laboratory animals.
AboutAbbreviations
ACSAmerican Cancer SocietyBaPbenzo(a)pyreneBBDbenign breast diseaseBCISbreast carcinoma in situBHAbutylated hydroxyanisoleBMIbody mass indexBPbenzo(a)pyreneBZBallschmiter & Zell 1980; refers to a naming convention for PCB congenersCBCRPCalifornia Breast Cancer Research ProgramCIconfidence intervalCLconfidence limitsDCISductal carcinoma in situDDEdichlorodiphenyldichloroethyleneDDTdichlorodiphenyltrichloroethaneDNAdeoxyribonucleic acidDODUS Department of DefenseDRZdiagonal radioactive zoneEDCendocrine disrupting chemicalELISAenzyme-linked immunosorbent assayERestrogen receptorETOethylene oxideHCBhexachlorobenzeneHCHhexachlorohexaneHEheptachlor epoxideHPCBhigher polychlorinated biphenylHRThormone replacement therapyLCISlobular carcinoma in situLPCBlower polychlorinated biphenylMORmortality odds ratioNCINational Cancer InstituteNHLnon-Hodgkins lymphomaNIEHSNational Institute of Environmental Health SciencesNIOSHNational Institute for Occupational Safety and HealthOCorganochlorineOCDoxychlordaneOCDDoctachlorodibenzo-p-dioxinODoptical densityORodds ratioOSHAOccupational Safety and Health AdministrationPAHpolycyclic aromatic hydrocarbonPBDEpolybrominated diphenyl etherPCBpolychlorinated biphenylPCDDpolychlorinated dibenzo[p]dioxinPCDFpolychlorinated dibenzofuransPCEperchloroethylenePCMRproportionate cancer morbidity ratioPIRproportional incidence ratioPMRproportionate morbidity ratioPRprogesterone receptorRDDrelative delivered doseRRrelative riskSDstandard deviationSESsocio-economic statusSIRstandardized incidence ratioSMbRstandardized morbidity ratioSMRstandardized mortality ratioTCDDdioxinTCEtrichloroethyleneTEQtoxic equivalentsTEXBtotal effective xenoestrogen burdenTNCtrans-nonachlorTSPtotal suspended particulatesWHRwaist-hip ratio