Environment and Breast Cancer: Science Review



Acrylamide, a chemical shown to cause mammary tumors in female rats, is formed during the heating of starch-rich foods to high temperatures.
Evidence From Humans
 
Abbreviations
ACS
American Cancer Society
BaP
benzo(a)pyrene
BBD
benign breast disease
BCIS
breast carcinoma in situ
BHA
butylated hydroxyanisole
BMI
body mass index
BP
benzo(a)pyrene
BZ
Ballschmiter & Zell 1980; refers to a naming convention for PCB congeners
CBCRP
California Breast Cancer Research Program
CI
confidence interval
CL
confidence limits
DCIS
ductal carcinoma in situ
DDE
dichlorodiphenyldichloroethylene
DDT
dichlorodiphenyltrichloroethane
DNA
deoxyribonucleic acid
DOD
US Department of Defense
DRZ
diagonal radioactive zone
EDC
endocrine disrupting chemical
ELISA
enzyme-linked immunosorbent assay
ER
estrogen receptor
ETO
ethylene oxide
HCB
hexachlorobenzene
HCH
hexachlorohexane
HE
heptachlor epoxide
HPCB
higher polychlorinated biphenyl
HRT
hormone replacement therapy
LCIS
lobular carcinoma in situ
LPCB
lower polychlorinated biphenyl
MOR
mortality odds ratio
NCI
National Cancer Institute
NHL
non-Hodgkins lymphoma
NIEHS
National Institute of Environmental Health Sciences
NIOSH
National Institute for Occupational Safety and Health
OC
organochlorine
OCD
oxychlordane
OCDD
octachlorodibenzo-p-dioxin
OD
optical density
OR
odds ratio
OSHA
Occupational Safety and Health Administration
PAH
polycyclic aromatic hydrocarbon
PBDE
polybrominated diphenyl ether
PCB
polychlorinated biphenyl
PCDD
polychlorinated dibenzo[p]dioxin
PCDF
polychlorinated dibenzofurans
PCE
perchloroethylene
PCMR
proportionate cancer morbidity ratio
PIR
proportional incidence ratio
PMR
proportionate morbidity ratio
PR
progesterone receptor
RDD
relative delivered dose
RR
relative risk
SD
standard deviation
SES
socio-economic status
SIR
standardized incidence ratio
SMbR
standardized morbidity ratio
SMR
standardized mortality ratio
TCDD
dioxin
TCE
trichloroethylene
TEQ
toxic equivalents
TEXB
total effective xenoestrogen burden
TNC
trans-nonachlor
TSP
total suspended particulates
WHR
waist-hip ratio