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1,2-dibromo-3-chloropropane
CAS RN 96-12-8



Cancer studies: Mammary gland tumors
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Originating list
The list(s) or database(s) in which the chemical was identified as showing an increase in mammary gland tumors. CPDB: Carcinogenic Potency Database, IARC: International Agency for Research on Chemicals Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man summaries, NTP TR: National Toxicology Program (NTP) Technical Reports, NTP 11ROC: NTP 11th Report on Carcinogens, CCRIS: Chemical Carcinogenesis Research Information Service.
Carcinogenicity Potency Database, IARC Monographs, National Toxicology Program studies, National Toxicology Program 11th Report on Carcinogens, Chemical Carcinogenesis Research Information System
Mammary gland tumor summary
A summary of findings related to mammary gland tumors, most often excerpted from IARC Monographs or the NTP 11th ROC, and, in some cases, supplemented by our evaluation of individual studies and reviews, is available for the priority chemicals and 67 others.
NTP 11ROC: When administered by gavage, 1,2-dibromo-3-chloropropane induced carcinomas of the mammary gland in female rats.
Citations to review sources and individual studies reporting mammary gland tumors are listed below.
Citation
Source Type
Notes
International Agency for Research on Cancer, Monographs on the evaluation of carcinogenic risk of chemicals to man.VOL.: 71 (1999) (p. 479) 1,2-Dibromo-3-Chloropropane.
Review
After oral administration, produced adenocarcinomas of the mammary gland in female rats.
Carcinogenic Potency Database 2005. Gold LS ST, Manley NB, Garfinkel GB, Ames BN. Summary Table by Chemical of Carcinogenicity Results in CPDB on 1485 Chemicals. 2005
Review
Two of two studies reported mammary tumors: NTP TR 206 and NTP TR28.
National Toxicology Program 11th Report on Carcinogens. 1,2-Dibromo-3-Chloropropane
Review
When administered by gavage, induced carcinomas of the mammary gland in female rats (NCI 1978).
National Toxicology Program Technical Report 206, 1982
Primary Literature
Has a second NTP Technical Report: TR28, 1978
National Toxicology Program Technical Report 28, 1978
Primary Literature